How to Layer Peptide Serums Into Your Routine

Apply peptide serums on clean skin before moisturizer, starting with lower concentrations and building up over weeks.

Peptides are the intelligent person's anti-aging ingredient—they work quietly and effectively without the drama of acids or the commitment of retinoids.

1. Start with clean, dry skin. Cleanse thoroughly and pat dry. Peptides absorb best on completely clean skin without any barrier from oils or previous products.
2. Apply peptide serum first. Use 3-4 drops and press gently into skin with fingertips. Peptides work best when they can penetrate deeply, so they go before heavier products.
3. Wait, then layer moisturizer. Give the serum 2-3 minutes to absorb before applying moisturizer. This prevents pilling and ensures the peptides actually reach your skin.
4. Build tolerance gradually. Start using peptides every other night for the first two weeks. Some people experience mild irritation initially as skin adjusts to increased protein synthesis.